Improved Synthesis Planning in Reaxys

Please find below the latest release notes for the September 2021 release.

This release includes a complete redesign of our synthesis planning environment. The new Retrosynthesis feature allows chemists to start their retrosynthesis projects by drawing the desired compound, provides in one view all the information needed to decide which route to take to the lab and enables project management and options for easier collaboration.

Users can now: 

• Easily search for relevant synthesis route for a known substance (published retrosynthesis)
• Users can organize their retrosynthesis projects in the central projects space and easily access:

  • Literature references for each reaction step
  • Reaction condition and experimental procedure
  • Commercial availability of starting materials
  • Export retrosynthesis route data in multiple formats

What is included in the current release:

• Redesign of Synthesis Planner to Retrosynthesis enabling users to launch a retrosynthesis search from ChemDraw JS or Marvin JS drawing tool
• Intuitive visualisation options with relevant literature references easily accessible to enable informed decision making
• Option to seamlessly integrate Reaxys predictive retrosynthesis module (additional subscription required).

What’s next 

• Further development to enable users to extend / edit the synthesis route giving them the ability to add new steps at any stage of the synthesis tree and to also remove single steps or complete branches